Rosmarie Friemann

 

Group members

Visiting address: Lundberg laboratory, Medicinaregatan 9 C, room 1209, 413 90 Gothenburg

Rosmarie Friemann  Principal investigator, Ph.D.  +46 (0)31-786 39 36   This e-mail address is being protected from spambots. You need JavaScript enabled to view it.
Rhawnie Caing-Carlsson  Ph.D. student  +46 (0)31-786 39 41   This e-mail address is being protected from spambots. You need JavaScript enabled to view it.
Parveen Goyal  Postdoc, Ph.D.  +46-(0)31-786 39 17   This e-mail address is being protected from spambots. You need JavaScript enabled to view it.
Elin Johansson  Ph.D. student  +46 (0)31-786 39 44   This e-mail address is being protected from spambots. You need JavaScript enabled to view it.
Weixiao Yuan Wahlgren  Postdoc, Ph.D.  +46-(0)31-786 39 17   This e-mail address is being protected from spambots. You need JavaScript enabled to view it.
Nasha Adhem  Master student   This e-mail address is being protected from spambots. You need JavaScript enabled to view it.
Elin Claesson  Master student

Former group members:

Karl Almén Burman  Master student  Chalmers  2011
Leah Kago  Master student  Chalmers  2011-2012
Annika Simonsson  Project student  University of Gothenburg   2014

 

Funding

We are currently supported by:

     

             

 

Publications

  1. Subangstrom resolution x-ray structure details aquaporin-water interactions. Kosinska Eriksson U, Fischer G, Friemann R, Enkavi G, Tajkhorshid E, Neutze R, Science 340: 1346-9 (2013).
  2. The unexpected T-cell recognition of an altered peptide ligand is driven by reversed thermodynamics. Allerbring EB, Duru AD, Uchtenhagen H, Madhurantakam C, Tomek MB, Grimm S, Mazumdar PA, Friemann R, Uhlin M, Sandalova T, Nygren P-Å, Achour A, Eur J Immunol. 42 (11): 2990-3000 (2012). 
  3. Structure of the Fab fragment of the anti-murine EGFR antibody 7A7 and exploration of its receptor binding site. Talavera A, Mackenzie J, Garrido G, Friemann R, López-Requena A, Moreno E, Krengel U, Mol Immun 48 (12-13):1578-85 (2011).
  4. Crystal structure of the HIV-2 neutralizing Fab fragment 7C8 with high specificity to the V3 region of gp125, Uchtenhagen H, Friemann R, Raszewski G, Spetz A-L, Nilsson L, Achour A, PLoS ONE 6 (4): e18767 (2011).
  5. MD simulations of a membrane protein-micelle complex in vacuo, Friemann R, Larsson D, Wang Y, van der Spoel D,  J Am Chem Soc 131: 16606-7  (2009).
  6. Nimotuzumab, an anti-tumor antibody that targets the EGFR, blocks ligand binding while permitting the active receptor conformation, Talavera A, Friemann R, Gómez-Puerta S, Martinez-Fleites C, Garrido G, Rabaza A, Lopez-Requena A, Amaury P, Johansen RF, Sánchez O, Krengel U, Moreno E, Cancer Res, 69: 1301-13 (2009).
  7. Production, purification, crystallization and preliminary X-ray diffraction analysis of the HIV-2-neutralizing V3 loop-specific Fab fragment 7C8, Uchtenhagen H, Sourial S, Friemann R, Ehnlund M, Spetz A-L, Harris RA, Madhurantakam C & Achour A, Acta Cryst F 65: 705-8 (2009).
  8. Structures of the Multicomponent Rieske Non-Heme Iron 2,3-Toluene Dioxygenase Enzyme System, Friemann R, Lee K, Brown EN, Gibson DT, Eklund H, Ramaswamy S, Acta Cryst D 65: 24-33 (journal cover) (2009).
  9. Determining Rieske Cluster Reduction Potentials, Brown EN, Friemann R, Karlsson A, Parales JV, Ramaswamy S, J Biol Inorg Chem 8: 1301-13 (2008).
  10. Structural Snapshots along the Reaction Pathway of Ferredoxin:Thioredoxin Reductase, Dai S, Friemann R, Glauser DA, Bourquin F, Manieri W, Shürmann P, Eklund H, Nature 448: 92-6 (2007).
  11. Active site residues controlling substrate specificity in 2-nitrotoluene dioxygenase from Acidovorax sp. strain JS42, Lee KS, Parales JV, Friemann R, Parales RE, J Ind Microbiol Biotechnol 10: 465-73 (2005).
  12. Purification, crystallization and preliminary X-ray diffraction studies of the three components of the toluene 2,3-dioxygenase enzyme system, Lee K, Friemann R, Gibson DT, Ramaswamy S, Acta Cryst F 61: 669-72 (2005).
  13. Purification, characterization, and crystallization of the components of the nitrobenzene and 2-nitrotoluene dioxygenase enzyme systems, Parales RE, Huang R, Yu CL, Parales J, Lee FKN, Lessner DJ, Ivkovic-Jensen MM, Liu W, Friemann R, Ramaswamy S, Gibson DT, Appl Environ Microb 71: 3806-14 (2005).
  14. Structural insights into the dioxygenation of nitroarene compounds: The crystal structure of nitrobenzene dioxygenase, Friemann R, Ivkovic-Jensen MM, Lessner DJ, Yu CL, Gibson DT, ParalesRE, Eklund H, Ramaswamy S, J Mol Biol 348: 1139-51 (2005).
  15. Structure of thioredoxin from Trypanosoma brucei brucei, Friemann R, Schmidt H, Ramaswamy S, Forstner M, Krauth-Siegel RL, Eklund H, FEBS Letters 554: 301-5 (2003).
  16. Crystal structure of plant pectin methylesterase, Johansson K, El-Ahmad M, Friemann R, Jörnvall H, Markovic O, Eklund H, FEBS Letters 514: 243-9 (2002).